Top Healthcare Startups

Discover & connect with the top healthcare startups that have recently raised venture capital funding.

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Top 20 Healthcare Startups to Watch

Is there anything more important to us than our health? The healthcare industry has come a long way over the years, especially with the continued advancements in technology. Medtech was at the forefront of the global fight against COVID-19 as we saw how companies were able to formulate vaccines and other treatments within months. 


But healthcare isn’t just about treatments and medications. Advancing medtech devices have allowed us to work on the preventative aspect of diseases and immunology. Catching diseases and illnesses before they even take shape will not only improve our overall quality of life, but take the burden and costs off of our healthcare system. 


As investors, healthcare stocks can often be a boom or bust industry to invest in. Since most companies depend on licensing and patents for their technology and treatments, clinical studies and trials are crucial to the success of the business. It’s often difficult to determine which companies will survive, but when you manage to pick the right ones, the return on investment can last for decades. 


Startup companies are in the early stages of raising capital and investments to further grow their business. HIstorically, investing in companies at the startup phase of their business cycle has been extremely profitable for early investors. This captures all of the major milestones for the company, including a potential IPO as well as initial product launches. For those of you who are bullish on the future of the healthcare industry, here are 20 of the best startup companies to add to your watchlist.


MediBuddy

MediBuddy is India’s largest digital healthcare platform which provides end to end solutions for the more than 1.4 billion residents of the world’s second largest country. More than just a telehealth app, MediBuddy provides 24/7 access to physicians with the added features of being able to book lab testings, delivering medicine to your front door, and providing pre and post-op care for surgeries. MediBuddy even takes care of the hassle of dealing with medical insurance and assists its users in setting it up. The company has even started to establish their own branded clinics where users can if a digital consultation is not enough.

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NexHealth

NexHealth

NexHealth has a goal of creating the perfect end to end digital experience for both physicians and patients. The company is a medical software company that builds APIs that allow individual practices to build out a fully customizable and unique program. These platforms automate mundane tasks like booking appointments, creating health files for new patients, and even taking notes for doctors.

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Workit Health

Workit Health is a revolutionary concept in the world of addiction treatment. Its virtual care platform allows users to recover from serious addictions in the comfort of their own home. Workit Health includes virtual calls with physicians, prescriptions sent directly to your local pharmacy, and an online community that helps users overcome addiction step by step. Best of all, Workit Health is accepted by major insurance companies like UnitedHealth, Humana, and Blue Cross. Workit Health boasts an 85% success rate in treating addictions compared to just 25% at an in-person detox facility. The company raised $118 million in its most recent Series C funding at the end of 2021.

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Korro Bio

Korro Bio is an RNA-editing company that is focused on developing novel genetic medicines through its OPERA (Oligonucleotide Promoted Editing of RNA) platform. Genetic editing is in its infancy, but following a major breakthrough by Intellia Therapeutics (NASDAQ:NTLA), the industry has been of keen interest to the investing community. With OPERA, Korro Bio is hoping to create viable new treatments for patients, specifically for genetic diseases that affect the liver, the eye, and the central nervous system. The company is looking to create precise edits to human RNA strands in vivo, without the need to permanently modify our genomic map. Korro Bio raised $116 million in January during its Series B funding round.

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Athletic Greens

So much of our health is affected by our diets and what we consume throughout the day. Athletic Greens is a New York-based company that was founded in 2010 and is targeting the estimated $7 trillion global health and wellness market. At its core, Athletic Greens is a nutritional drink where one scoop per day can provide you with an entire regiment of supplements, multivitamins, and non-dairy probiotics. Athletic Greens promotes some of the most overlooked areas of personal health such as gut health, immunity, energy, and recovery. Athletic Greens recently brought on former Focus Brands executive and food and beverage industry star, Kat Cole as its new President and COO. It also has starpower backing the product with celebrities like Hugh Jackman, Steve Aoki, and Joe Rogan as users and investors. Athletic Greens completed a Venture Round of funding worth $115 million with a valuation of $1.2 billion in January.

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IntelyCare

IntelyCare is a revolutionary idea for tackling staffing shortages in the nursing industry. The company has built an AI-based platform that pairs nursing professionals with available and unfilled assignments at over 1,600 organizations around the US. This allows nurses to build their own schedule based around their own lives, rather than being at the mercy of a hospital scheduler. This allows hospitals to increase their staffing resources while cutting down on added costs like overtime, as well as fatigue or potential injuries. IntelyCare has already helped over 30,000 nurses in 28 states, and witnessed a 300% growth in revenue for the fiscal year 2021. The company also completed a Series C round of funding valued at $115 million in April of this year.

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Sionna Therapeutics

Sionna Therapeutics is a brand new company having only been established in 2019. That didn’t prevent Sionna from securing a Series B funding round worth $111 million in April. Sionna is focussed on not only finding a treatment for the genetic disease cystic fibrosis, but it is also looking to restore normal CFTR function. CFTR or the Cystic Fibrosis Transmembrane Conductance Regulator gene, is directly related to the degradation of cystic fibrosis patient health. It is the first novel program targeting the NBD-1 domain of the CFTR gene. Major investors in Sionna include Orbimed, Atlas Venture, and the sovereign wealth fund of Qatar.

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Nomi Health

Nomi Health is certainly a novel take on the traditional healthcare system in the US. Part health care provider, part fintech platform, Nomi Health is breaking down the barriers of what we think about our current medical system. ON the healthcare front, Nomi has created pop up health hubs around the country, multiple testing labs, and has over 2,500 doctors and nurses working for them. In terms of fintech, Nomi is seeking to reduce the cost of payments to employers, while at the same time speeding up the payments to providers. The pop up hubs took off during the pandemic, serving as vaccination and screening sites for COVID-19. Nomi is attempting to create a direct billing healthcare system that does not rely on the added costs of insurance or copays. The company completed a Series A funding round worth $110 million in December of last year.

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Scipher Medicine

Scipher Medicine is utilizing technologies like artificial intelligence to match patients with the most effective therapy based on genomic data. The Spectra platform continues to analyze patient data and molecular data sets to build stronger patient recommendations based on past treatment successes. Scipher has also developed Prism RA, a molecular signature test that can detect if a prescribed treatment will even work with the matched patient. Scipher can then work with pharmaceutical companies to help create drugs that have a higher rate of efficacy amongst biologically similar patients. In February of this year, Scipher completed a Series D round of funding worth $110 million.

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Geneoscopy

Geneoscopy is a St. Louis-based company that is developing new and improved diagnostic testing for the gastrointestinal system. By developing a non-invasive and preventative test for colorectal cancers, Geneoscopy is hoping to capture the market of patients who are unwilling to attend routine colonoscopies. Genescopy tests the human RNA found in stool samples as a way of detecting and preventing colorectal cancers. The company is currently undergoing a clinical study of 10,000 patients for which it is looking to achieve FDA approval for its RNA-FIT stool testing system. In November of 2021, Geneoscopy completed a Series B round of funding worth $105 million.

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Mindmaze

Mindmaze is a company based in Switzerland that is transforming the way we think about brain recovery. The company was established in 2012 and has been working on its mission to help patients recover from neurological diseases. Patients use Mindmaze’s FDA-cleared digital therapeutics which uses technologies like motion analytics, AI, and cloud technologies. Mindmaze helps patients with neurorehabilitation as well as brain repair following traumatic events like a stroke or diagnosis of Parkinson’s disease. In February, Mindmaze completed a Venture Round of funding worth $105 million.

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IsoPlexis

Although not technically a startup, the company is focused on the science of proteomics on a single-cell level, and builds instruments that can analyze the specific proteins secreted by our cells. What is the significance of this? Scientists can use this data to determine how well certain types of treatments, specifically those for cancers, will work in each individual patient. IsoPlexis is seeking out what they refer to as Superhero cells, which the company has identified as the key to bodies fighting off illnesses. These Superhero cells secrete more proteins, and a higher number of them has been correlated to a more persistent response to fighting off cancer. IsoPlexis insists that this single-cell proteomics provides data that was previously missed in existing cellular technology like flow cytometry. IsoPlexis had its final round of funding through a Series D raise that brought in $125 million. The company debuted on the NASDAQ exchange in October of 2021.

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Brightline

Brightline is the country’s first behavioral health platform that is focused on helping children, youth, and families. Its platform and community are virtual, with on demand availability of behavioral therapists, licensed psychiatrists, and personal coaches. There is support for the entire family as well, particularly for parents who are finding it increasingly difficult to navigate the world of teenage mental health and disabilities such as autism. Brightline recently closed out a Series C round of funding worth $105 million in April, 2022.

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Nalu Medical

Nalu Medical

Nalu Medical is a business that is creating cutting edge neurostimulation technologies for people who live with chronic pain. Its technology is an example of micro-IPG or micro-implantable pulse generator, which is used in spinal cord and peripheral nerve stimulations. The micro-IPG is implanted through a non-invasive procedure, and is 27 times smaller than the largest commercially available IPG. The implant is battery free which eliminates the need for battery replacement surgeries, and can be removed if no longer needed. Users control stimulations with their iOS or Android smartphone, through a system that already has FDA approval. In February, Nalu raised an Equity round of funding worth $104 million.

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Seismic Therapeutic

Seismic is a biotechnology company that is attempting to revolutionize the field of immunology therapies. Its IMPACT platform utilizes machine learning technology into the drug discovery process, creating a potentially unprecedented impact in the designer biologics and adaptive immune system fields, while minimizing immunogenicity. Seismic is able to discover, design, and make these drugs manufacturable for consumer use. In February of this year, Seismic raised a Series A funding round worth $101 million, with major investors like Lightspeed Venture Partners and Boxer Capital.

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Cadence Solutions

Cadence Solutions is yet another company that is adding remote and virtual services to the healthcare industry. The company’s mission is to ‘help health systems deliver world-class care outside the four walls of the hospital’. Cadence has a software platform that connects with health services to provide post-hospital care for patients recovering from diseases like heart failure, Type 2 diabetes, hypertension, and COPD. Cadence has a top tier leadership group with clinical leaders from Johns Hopkins University, Livongo, Oscar, and Cedar. In December of 2021, Cadence raised a Series B round of funding worth $100 million.

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Visby Medical

Visby Medical catapulted into the mainstream conversation when its PCR COVID-19 test kit was the first to receive Emergency Use Authorization by the FDA. The kit was a variation of its also FDA-approved sexual health test, which provides an accuracy reading of greater than 97% in less than 30 minutes. Visby is in the business of creating diagnostic tests for diseases that are portable and can be used by anyone. As viruses continue to have effects on the global population, Visby is anticipating a surge in demand for portable diagnostics test kits in the future. As are its investors as Visby closed a Series E funding round that brought in $100 million in March.

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Found

Found is a US-based company that is focused on weight loss and long-term weight care. Rather than just eating less and working out more, Found has formulated an actual science behind its weight loss program. The company focuses on things like neurobiology, hormone regulation, metabolism, microbes, medication, and genetics. As with many healthcare startups, Found is taking a virtual approach to weight loss. Working with certified medical practitioners and one on one health and diet coaches. Found will analyze and monitor your diet and exercise, as well as other important factors such as mental health and sleep patterns. In December of 2021, Found closed a Series B funding round worth $100 million.

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Clipboard Health

Not all healthcare startups are in the field of treatments or medical technology. Clipboard Health is an online marketplace for medical professionals who are looking to pick up additional shifts at other facilities. The Clipboard platform is available via a desktop or mobile app, and it is a two–way street as it can be used by both medical professionals and facilities who need extra help. Due to the around the clock nature of healthcare work, the Clipboard support team is available 24/7, with instant payment options via the fintech company Stripe. Clipboard is opening up the healthcare industry to flexible work schedules which can help prevent fatigue and stress amongst healthcare professionals. At the end of April, Clipboard completed a Series C round of funding worth $80 million.

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HotSpot Therapeutics

HotSpot Therapeutics targets proteins that it refers to as ‘natural hotspots’ in a revolutionary form of drug discovery. Hotspot medicines are powerful and provide a way of treating serious diseases through previously inaccessible pathways. Its Smart Allostery platform integrates machine learning technology and tailored chemistry to target diseases in new ways that have never been seen before. The company has identified over 1,500 protein hotspots that can be used to focus on new treatments and therapies for diseases like cancer. HotSpot raised a $100 million round of Series C funding back in November of 2021.

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